Research and Reports in Urology

Dove Medical Press is pleased to invite you to submit your research to an upcoming Article Collection on "Advancing Patient Safety Culture and Managing Healthcare Risks for Sustainable Healthcare", organized by Guest Advisor Werner T.W. de Riese in Research and Reports in Urology.

In recent years an evident paradigm shift has evolved across both local and systemic treatment choices for urologic malignancies. Regarding prostate cancer management, research has focused on a multitude of treatment options; whereas radical prostatectomy is well established for local disease, the role of pelvic lymph node dissection remains controversial, in particular in the context of metastatic disease on imaging. Adjuvant and early salvage radiotherapy offer distinct approaches, with recent studies indicating comparable outcomes. Systemic therapies continue to evolve as e.g., chemotherapy's role in radiation therapy is still an ongoing subject of clinical studies.

For locally advanced penile squamous cell carcinoma (PSCC), neoadjuvant chemotherapy and adjuvant therapy are actively explored as research is studying new drug regimens for first-line treatment options. While there are new and promising developments in understanding of cellular pathways and immune system targets for potential therapies, the results of limited trials are restricting their broad clinical application. Though the therapeutic achievements in systemic treatment of renal cell carcinoma currently rely on tyrosine kinase inhibitors with varying success, new certain immune checkpoint inhibitors are revealing very promising clinical results. Adjuvant therapy for urothelial carcinoma, in particular bladder cancer, has remained controversial in the literature, despite the proven effectiveness of neoadjuvant chemotherapy for muscle-invasive bladder cancer.

Practicing urologists and medical oncologists are often confronted with challenging clinical scenarios of urologic malignancies. Therefore, an update on recent advancements in the therapeutic outcome of difficult disease stages is appreciated as treating clinicians are ultimately driven to improve the chances of reducing disease burden, and thus improving patients’ survival. 

In this Collection, we are seeking original research articles as well as review papers. This Collection will include novel aspects of treatment options for urologic malignancies within the field of PSCC, prostate cancer, and bladder cancer. Among others, this collection will include primary discoveries as well as summaries of both adjuvant and neoadjuvant therapy, surgical treatment, use of checkpoint inhibitors, and hormonal therapy. The main goal and purpose of this Collection is bringing awareness about recent advancements for the different disease stages of these urologic malignancies.

All manuscripts submitted to this Article Collection will undergo desk assessment and peer-review as part of our standard editorial process. Please review the journal Aims and Scope and author submission instructions prior to submitting a manuscript.

The deadline for submissions is 3 May 2024.

Please submit your manuscript on our website, quoting the promo code XNJYG to indicate that your submission is for consideration in this Article Collection.

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Dove Medical Press is pleased to invite you to submit your research to an upcoming Article Collection on "Innovations in surgery for urological malignancies", organized by Guest Advisor Guglielmo Mantica in Research and Reports in Urology.

Urology is one of the most varied and heterogeneous specialties in the field of surgery. The particular conformation of the genitourinary system means that urological pathologies may require endoscopic, open, laparoscopic, robotic and reconstructive surgery treatments. This variability in surgical approaches also applies to the field of treatment of genitourinary neoplasms, and often means that urology is among the first to be influenced by technological evolution in the surgical field. 

For this reason, it is not difficult to understand how, in recent decades, urology has been one of the most innovative branches of the surgical field, in particular with the introduction of laparoscopy, robotic surgery, increasingly smaller endoscopes and powerful lasers. In recent years, the impact of new technologies has changed urological surgery and the surgical approach to tumors. 

The most striking example is that of robotic surgery, which is rapidly replacing laparoscopic surgery and has reduced open approaches to a minimum number. Furthermore, the continuous technological updating with single port platforms, the new robots available on the market, but also the new support devices, suturing instruments and hemostatic agents, are increasingly pushing the limits of minimally invasive surgery. An example of this are the nerve – sparing techniques for radical prostatectomy (RARP), or the renal surgery increasingly aimed at partial nephrectomy (RAPN) even for large tumors. 

Similarly, the increase in precision, ease of handling and caliber reduction of the endoscopes, together with the evolution of lasers, has also led to an increase in the number and quality of endoscopic treatments for genitourinary cancers. The benefits in this sense appear to be many: from obtaining en-bloc surgical specimens, which can be better assessed by the uro-pathologist, to the treatment of numerous tumors of the upper urinary tract (UTUC). 

This progressive and rapid change is impacting not only the management of the patient himself but also the training of trainees and young surgeons. Innovations have been presented also in this field, in order to better train the future generations of uro-oncological surgeons. 

In this special series we aim to provide an update of the current practical and technological innovations in the management of genitourinary neoplasms.

All manuscripts submitted to this Article Collection will undergo desk assessment and peer-review as part of our standard editorial process. Please review the journal Aims and Scope and author submission instructions prior to submitting a manuscript.

The deadline for submissions is 11 November 2024.

Please submit your manuscript on our website, quoting the promo code FEZWX to indicate that your submission is for consideration in this Article Collection. Please note normal Article Processing Charges will apply.

Guest Adviser

Dr. Guglielmo Mantica

Department of Urology, IRCCS Policlinico San Martino Hospital, Genoa, Italy

Dr. Guglielmo Mantica received his medical degree in 2011 at University of Insubria-Varese and his degree in urology at University of Genova in 2018. In 2017-2018 he attended a fellowship at Tygerberg Hospital–Stellenbosch University (Cape Town, South Africa) where he was able to increase his skills and knowledge in trauma surgery, endourology and reconstructive surgery with special focus on penile transplantation. From 2018 to 2019 he had been a consultant at San Raffaele Hospital (Milan, Italy). He is currently a urology consultant at Policlinico San Martino Hospital–University of Genova (Italy).

He has been an active member of urological societies since the beginning of his residency and he is currently a full member of EAU (European Society of Residents in Urology), YAU (Young Academic Urologists) Trauma and reconstructive urology group, associate panelist of EAU, Guidelines on Urological infections, and associate member of ESGURS (EAU Section of Genito-Urinary Reconstructive Surgeons).

His main interests are minimally invasive urology (robotic surgery and laparoscopy), endourology, trauma and reconstructive urology. He is author of about 130 peer-reviewed articles in international journals and 7 book chapters.

 

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